Visualizing Breakthroughs, Deeper Insights

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Learn How Our Animal Imaging Core Can Help

The Tufts Preclinical Imaging Core (PIC) provides equipment and expertise for in vivo and ex vivo molecular and anatomical imaging for basic research and translational studies in small animals. We offer a diverse array of imaging modalities, including optical imaging, ultrasound (US), micro-computed tomography (microCT), and EchoMRI. We also have a slit lamp and Phoenix Micron IV microscope for ophthalmic studies. These modalities capture physiological and anatomical data with a wide range of spatial and temporal resolutions and imaging depths, ensuring we can support most preclinical studies. Our instruments are available both for self or technician assisted service.

The PIC not only supports research at Tufts University and affiliated hospitals, it also offers a wide range of contract research services for Biotech and Pharma. Our micro-CT is also available to materials science researchers and ex vivo work on larger animals.

Our services include: Equipment Training, Analysis Software Training, Assisted & Unassisted Imaging, Study Design/IACUC protocol consulting, and Data Post-Processing/Analysis

For confocal microscopy, please refer to the Tufts Imaging and Cell Analysis Core on the Boston Campus, and the Tufts Advanced Microscopic Imaging Center on the Medford campus.

Check Out Our Equipment Gallery

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Optical Imaging (IVIS)

PerkinElmer IVIS Spectrum: Advanced in vivo imaging system designed for non-invasive tracking of disease progression, cell trafficking, and gene expression. Capable of bioluminescence and fluorescence imaging with high sensitivity, supporting preclinical research at Tufts CMS. Available for assisted and unassisted imaging.

Check Out The IVIS Spec Sheet

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Micro-Computed Tomography (microCT or uCT)

Bruker Skyscan 1176: Advanced microCT system for non-invasive volumetric imaging using X-rays. Applications include bone densitometry, morphometry, dental analysis, and lung imaging. A powerful tool for detailed cross-sectional and 3D renderings in preclinical research at Tufts CMS. Available for assisted and unassisted imaging.

Check Out The Skyscan 1176 Spec Sheet

Colorful background bars with a cutout of the VisualSonics VEVO 2100 ultrasound system, displaying an example of its high-resolution imaging output of organs and tissues.

Ultrasound (US) 

VisualSonics VEVO 2100: High-frequency ultrasound imaging system for dynamic visualization of organs, tissues, and blood flow. Ideal for applications such as cardiac function analysis, tumor monitoring, guided injections, and targeted therapy treatments. Available for assisted and unassisted imaging.

Check Out The VEVO 2100 Spec Sheet

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EchoMRI

EchoMRI-100 and EchoMRI-900: Non-invasive systems for whole-body composition analysis, measuring fat, lean mass, and free water without requiring anesthesia. Essential for precise and humane preclinical studies at Tufts CMS. Available for assisted and unassisted imaging.

Check Out The EchoMRI Spec Sheet

Colorful background bars with a cutout of the Micron IV ophthalmic imaging system, featuring an example of its color fundus and fluorescent imaging output.

Micron IV

Micron IV: Advanced ophthalmic imaging system for in vivo eye and brain research. Capable of color fundus and fluorescent imaging with an image-guided laser attachment, supporting precise preclinical ophthalmic studies at Tufts CMS.
 

Check Out The Micron IV Spec Sheet

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Slit Lamp

Slit Lamp: Specialized ophthalmic tool for anterior and posterior segment imaging in preclinical eye research. Provides detailed visualization of ocular structures to support advanced studies at Tufts CMS.

Preclinical Imaging Core Resources

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